Evidence supporting the use of: Zinc
For the health condition: Fatty Liver Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Zinc is increasingly being investigated for its potential role in supporting or treating non-alcoholic fatty liver disease (NAFLD). A growing body of scientific literature suggests that zinc may have beneficial effects on liver health, primarily due to its antioxidant, anti-inflammatory, and insulin-sensitizing properties. Several preclinical studies in animal models of fatty liver disease have shown that zinc supplementation can reduce hepatic steatosis, decrease oxidative stress, and improve liver function tests. These effects are thought to be due to zinc’s role in modulating lipid metabolism, reducing inflammatory cytokines, and improving insulin resistance—key factors in the pathogenesis of NAFLD.
Human evidence, however, remains limited. A few small clinical trials and observational studies have reported lower serum zinc levels in patients with NAFLD compared to healthy controls, and some pilot supplementation studies have demonstrated improvements in liver enzymes and markers of inflammation. Nonetheless, these studies are generally small, have short durations, and often lack robust control groups. Major liver society guidelines do not currently recommend zinc as a standard treatment for fatty liver disease, citing insufficient high-quality evidence.
In summary, while there is some scientific rationale and early-stage experimental evidence suggesting zinc may benefit patients with fatty liver disease, the clinical evidence is not yet strong. Its use can be considered experimental and should not replace established treatments such as dietary modification, exercise, and management of metabolic risk factors.
Other ingredients used for Fatty Liver Disease
4-hydroxyisoleucine7,14-Hydroxy-Docosapentaenoic Acid
Acacetin
Adzuki bean
Akkermansia muciniphila
Algae
algal oil
Algal protein
Alisma
Alpha methyl tetradecylthioacetic acid
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
Anemarrhena
anemarrhena asphodeloides
anthocyanins
Antrodia camphorata
apigenin
apocynin
arabinoxylan
argan nut oil
arjun tree
arjuna
Arjunolic acid
Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
astaxanthin
astragaloside
avocado
baicalein
baicalin
banaba
barberry
barley
beet
berberine
Berberis (unspecified)
betanin
Bifidobacteria
Bifidobacterium bifidum
Bifidobacterium longum
bile acid
black garlic
Blakeslea trispora
borotutu
branched-chain amino acids
Brassica
Brown Algae
brutieridin
butyrate triglyceride
butyric acid
camelina oil
carnosic acid
carqueja
catechins
caterpillar mushroom
Caulerpa okamurae
cauliflower
chebulic acid
chia seed
chicory
Chitin-Glucan Complex
chlorella
chlorogenic acid
chokeberry
choline
coix
conjugated linoleic acid (CLA)
copalchi
coriander
corilagin
corosolic acid
crocetin
cruciferous
Curcuma
curcumin
cyclodextrin
cynarin
cynaropicrin
D-Pinitol
dandelion
danshen
decursin
diallyl disulfide (DADS)
diallyl sulfide
dihydromyricetin
diosgenin
dithiolthiones
DL-Methionine
eicosapentaenoic acid
Enicostemma littorale
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
erythrodiol
Eucommia ulmoides
fatty acids
fenugreek
ferulic acid
fiber
fiber blend (proprietary)
fish oil
fish protein
flavanones
flavonolignan
flavonols
flaxseed
fucoidan
fucosterol
fucoxanthin
ganoderma
ginger
Glutathione
grape
hesperetin
hydroxycinnamic acid
hydroxytyrosol
isosilybin
Jaboticaba
jiaogulan
Job\'s tears
Jurubeba
Kefir
kelp
l-carnitine
L-glutathione
L-methionine
L-taurine
Lactobacillus plantarum
lecithin
Legume protein
licorice root
limonoid
lingzhi
liquid liver fractions
Lycium
mangiferin
Marine fat
Marine lipid
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Morus
Mulberry
Myricetin
Naringenin
Naringin
Niacin (vitamin B3)
nicotinamide riboside
nopal
oleanolic acid
oleic acid
Oleoylethanolamide
Oleuropein
Oligosaccharides
olive
omega-3 fatty acids
omega-9 fatty acids
oolong tea
ornithine L-aspartic acid
Osthole
Oxymatrine
palmitoleic acid
perilla
Phaeophyceae
Phellodendron
phenolic compounds
phlorizin
phlorotannins
phosphatidylcholine
phospholipids
Phthalides
picrorhiza kurroa
Pinitol
Polydatin
polyphenols
prebiotic blend (proprietary)
psyllium
pu-er tea
Puerarin
punarnava
punicalagins
purple tea
rapeseed oil
Rebaudioside
reishi mushroom
resveratrol
rhubarb
S-allylcysteine
Salacia
Salvianolic acid
Schisandrins
Schizochytrium
Schizochytrium Oil
seaweed
sesame
Sesamin
Silybin
Silychristin
Silydianin
silymarin
Sinensetin
spirulina
Syringic acid
Tangeretin
Tanshinone
Taurine
Taxifolin
Tetradecylthioacetic acid
Theabrownin
Thistle
tocotrienols
Trans-pterostilbene
Trehalose
tributyrin
Trimethylglycine (TMG)
Triphala
turmeric
Tyrosol
Urolithin A
Ursolic Acid
Varuna
vitamin C
vitamin E
Wakame
Walnut
Wax Gourd
Yacon
Yin Chen
Zinc
Zucchini
β-nicotinamide mononucleotide (NMN)
Other health conditions supported by Zinc
AbrasionsAcne
Acquired Immune Deficiency Syndrome
Aging (prevention)
Alcoholism
Anemia
Anorexia
Antibiotics (alternatives to)
Anxiety
Anxiety Disorders
Appetite (deficient)
Arthritis
Athlete's Foot
Attention Deficit Disorder
Autism
Autoimmune Disorders
Benign Prostate Hyperplasia
Birth Defects (prevention)
Bites and Stings
Blisters
Body Building
Body Odor
Boils
Broken Bones
Bruises (healing)
Bulimia
Burns and Scalds
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiovascular Disease
Cartilage Damage
Cataracts
Celiac Disease
Cervical Dysplasia
Chemotherapy (reducing side effects)
Cholera
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colitis
Concentration (poor)
Congestion
Congestive Heart Failure
Conjunctivitis
Contagious Diseases
Convalescence
Copper Toxicity
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cradle Cap
Cramps (menstrual)
Crohn's Disease
Cuts
Cystic Fibrosis
Dandruff
Debility
Dehydration
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Diaper Rash
Diarrhea
Digestion (poor)
Duodenal Ulcers
Dysentery
Eczema
Endometriosis
Energy (lack of)
Enteritis
Epstein Barr Virus
Erectile Dysfunction
Exercise
Eye Infections
Eye Problems
Eyes (red or itching)
Eyes (spots before)
Eyesight (poor)
Failure to Thrive
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Fingernails (weak or brittle)
Foot Odor
Free Radical Damage
Gastritis
Giardia
Gingivitis
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hashimoto's Disease
Hearing Loss
Heart (weakness)
Heavy Metal Poisoning
Hemochromatosis
Hemorrhoids
Hepatitis
Herpes
Hypothyroid
Impetigo
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Insomnia
Irritability
Irritable Bowel Syndrome
Itching
Itching (rectal)
Jock Itch
Labor and Delivery
Lead Poisoning
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lupus
Macular Degeneration
Mastitis
Measles
Memory and Brain Function
Menorrhagia
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mononucleosis
Mood Swings
Nerve Damage
Nervous Exhaustion
Night Blindness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pancreatitis
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Poison Ivy or Oak
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Premature Ejaculation
Progesterone (low)
Prostatitis
Protein Digestion (poor)
Psoriasis
Puberty (hormone balancer)
Rashes and Hives
Rhinitis
Rosacea
Scars / Scar Tissue
Schizophrenia
Scratches and Abrasions
Seborrhea
Sex Drive (low)
Shingles
Sickle Cell Anemia
Sinus Infection
Skin (dry and/or flaky)
Skin (infections)
Skin (oily)
Skin Care (general)
Sleep (restless and disturbed)
Small Intestinal Bacterial Overgrowth
Smell (loss of)
Sore or Geographic Tongue
Sore Throat
Stress
Stye
Sugar Cravings
Sunburn
Surgery (healing from)
Surgery (preparation for)
Syphilis
Teeth (loose)
Testosterone (low)
Thinking (cloudy)
Tickle in Throat
Tonsillitis
Tooth Decay
Toxemia
Triglycerides (high)
Tuberculosis
Ulcerations (external)
Ulcers
Vitiligo
Warts
Wasting
Worry
Wounds and Sores
Products containing Zinc
Nature's Sunshine Love and Peas (Sugar Free Original Formula)
Nature's Sunshine 5-HTP Power
Nature's Sunshine Adrenal Support
Nature's Sunshine AnxiousLess
Nature's Sunshine AnxiousLess
Nature's Sunshine Bowel Detox
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Candida Clear
Nature's Sunshine Cellular Energy
Nature's Sunshine Children's Elderberry Immune
Nature's Sunshine Children's MultiVitamin & Mineral
Nature's Sunshine Defense Maintenance
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Glandular System
Nature's Sunshine Love and Peas (Sugar Free) NEW!
Nature's Sunshine Love and Peas
Nature's Sunshine Master Gland Formula®
Nature's Sunshine Mega-Chel
Nature's Sunshine Men's Formula (With Lycopene)
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Nature's Harvest
Nature's Sunshine Perfect Eyes
Nature's Sunshine Power Greens Pouch
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Power Meal Chocolate
Nature's Sunshine Power Meal Vanilla
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Immune
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Target TS-II Formula
Nature's Sunshine Thyroid Support
Nature's Sunshine Ultrabiome DTX
Nature's Sunshine VitaWave
Nature's Sunshine Yeast/Fungal Detox
Nature's Sunshine Zinc
Nature's Sunshine Zinc Lozenge
