Evidence supporting the use of: Trace minerals
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Trace minerals, including iron, zinc, selenium, copper, manganese, iodine, and others, play essential roles in numerous biochemical pathways critical for energy production and metabolism. The most studied link is between iron and energy: iron deficiency leads to anemia, resulting in fatigue and reduced energy because of impaired oxygen transport. Supplementing with iron is clinically validated to improve energy in those who are deficient. Other trace minerals like zinc and selenium are cofactors in mitochondrial enzymes that influence ATP production, but evidence supporting supplementation for boosting energy in the absence of deficiency is limited. Some studies have investigated combinations of trace minerals and vitamins in individuals with fatigue, with mixed results. The consensus is that supplementation of trace minerals can support energy levels if there is an underlying deficiency, but routine use in healthy individuals for energy enhancement lacks strong scientific support. Historical traditions of mineral supplementation exist in various cultures, but modern use is largely anchored in the correction of deficiencies rather than direct energizing effects. In summary, there is scientific validation for the use of trace minerals (especially iron) in treating fatigue caused by deficiency, but little high-quality evidence for benefits in people with normal levels.

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acetyl l-carnitine
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alpha d-ribofuranose
alpha-ketoglutarate (AKG)
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capsaicinoids
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coenzyme Q10 (CoQ10)
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l-glycine
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malic acid
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microbial enzymes (proprietary)
milk
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nettle
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pollen
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berry
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cola nut
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