Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (specifically, the form beta-tocopherol, though most studies use alpha-tocopherol) has some scientific backing for its use in supporting or treating eczema (atopic dermatitis), but the evidence is limited and not robust. A few small clinical trials and observational studies have suggested that oral or topical Vitamin E may help reduce eczema symptoms such as itching, erythema, and lesion severity, likely due to its antioxidant and anti-inflammatory properties. For instance, a double-blind placebo-controlled trial (Jaffary et al., 2015) found that oral Vitamin E supplementation reduced the severity of atopic dermatitis symptoms in adults. Another pilot study (Tsoureli-Nikita et al., 2002) indicated that Vitamin E supplementation improved clinical eczema scores compared to placebo. However, most of these studies have been small, short in duration, and have methodological limitations.

There is no strong historical or traditional use of Vitamin E specifically for eczema, and most recommendations stem from modern interest in antioxidants. Systematic reviews and guidelines typically do not list Vitamin E as a first-line or proven therapy for eczema, but note it may be considered as an adjunct in some cases. Overall, the evidence is suggestive but far from conclusive, and more rigorous, large-scale studies are needed to establish efficacy and optimal dosing.

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