Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sphaeranthus indicus, commonly known as East Indian Globe Thistle or Mundi, is a plant widely used in traditional Ayurvedic and Unani medicine for various skin disorders, including eczema. The traditional use stems from its reputed anti-inflammatory, antimicrobial, and antipruritic (anti-itch) properties. Several ancient texts and ethnobotanical surveys mention its use as a paste or decoction applied topically to relieve symptoms of eczema, such as redness, itching, and irritation.

Scientific evidence supporting its efficacy in eczema is limited. Some preliminary in vitro and animal studies have indicated that extracts of Sphaeranthus indicus exhibit anti-inflammatory and antioxidant activities, which could theoretically benefit inflammatory skin conditions. For example, a few studies have documented the presence of bioactive compounds like flavonoids, eudesmanolides, and essential oils, contributing to these effects. However, there is a lack of robust clinical trials, especially in human subjects with eczema, to conclusively validate these traditional claims.

In summary, while Sphaeranthus indicus has a long-standing traditional use for eczema and related skin disorders, scientific validation remains weak and primarily preclinical. Therefore, its use for eczema is justified mainly by tradition, with an evidence rating of 2/5 due to the lack of high-quality clinical data.

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