Evidence supporting the use of: Peony
For the health condition: Eczema

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Peony (Paeonia lactiflora root, often called "Bai Shao" in Traditional Chinese Medicine (TCM)) has a long history of use in East Asian herbal medicine for a variety of inflammatory and immune-related conditions, including skin ailments such as eczema. In TCM, peony is considered to have "cooling" and anti-inflammatory properties and is frequently included in multi-herb formulas designed to address "wind-dampness" or "heat in the blood," patterns that are sometimes associated with eczema and similar skin complaints. Historical texts and contemporary herbal compendia cite peony as a supportive herb for reducing itching, redness, and inflammation.

However, while its traditional use is well documented, direct modern clinical studies on peony's efficacy for eczema specifically are limited. Some laboratory and animal studies have investigated the anti-inflammatory and immunomodulatory effects of peony root extracts and their active compounds (such as paeoniflorin), showing potential mechanisms that could be relevant to eczema, such as inhibition of pro-inflammatory cytokines and reduction of histamine release. Nevertheless, robust clinical trials in humans with eczema are lacking.

In summary, the use of peony for eczema is primarily justified by traditional practice, with a modest scientific rationale based on laboratory and animal data but insufficient direct clinical evidence. The strength of evidence is therefore rated as 2 out of 5.

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