Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Linoleic acid (LA), an essential omega-6 fatty acid, has scientific evidence supporting its role in managing eczema (atopic dermatitis), though the strength of evidence is moderate. Eczema is characterized by a defective skin barrier and increased transepidermal water loss. LA is a critical component of ceramides and other lipids in the stratum corneum, which help maintain skin barrier integrity and moisture retention. Research has shown that patients with eczema often have reduced levels of LA in their skin, contributing to barrier dysfunction and inflammation.

Several clinical studies have evaluated topical and oral supplementation of LA and related fatty acids. Topical application of LA has demonstrated improvement in skin barrier function and reduction in symptoms such as dryness and scaling. Oral supplementation with oils rich in LA—like sunflower oil—has been shown in some studies to improve clinical outcomes in children and adults with eczema. However, results are mixed, and not all studies show significant benefit over placebo or other treatments.

Major dermatological guidelines acknowledge the potential benefit of LA-rich oils as adjuncts in eczema management, particularly as emollients. LA is generally safe and well-tolerated. While not a stand-alone treatment, its inclusion in skin care regimens for eczema is supported by biological plausibility and moderate clinical evidence. More high-quality randomized controlled trials are needed to strengthen the recommendation.

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Other ingredients used for Eczema

Other health conditions supported by linoleic acid (LA)

Products containing linoleic acid (LA)

Nature's Sunshine Evening Primrose Oil