Synopsis

Source of validity: Scientific
Rating (out of 5): 2

There is some scientific evidence supporting the use of Lactobacillus species in the management of eczema (atopic dermatitis), particularly in infants and children. Several clinical trials and meta-analyses have explored the effect of probiotics—including unspecified strains of Lactobacillus—on eczema symptoms and prevention. Some studies suggest that certain strains, such as Lactobacillus rhamnosus GG, may reduce the risk of developing eczema when given to pregnant women and infants at high risk, or may modestly improve symptoms in children with established eczema. However, the results are mixed, with other studies showing little or no benefit.

The mechanism by which Lactobacillus may help eczema is thought to involve modulation of the immune system and the gut microbiota, potentially reducing inflammation and improving skin barrier function. Nevertheless, the effects appear to be strain-specific, and not all Lactobacillus probiotics are equally effective. Major clinical guidelines do not currently recommend probiotics as a standard treatment for eczema, due to inconsistent findings and variability among strains and study designs.

In summary, while there is some scientific basis for the use of Lactobacillus in eczema prevention and management, the overall evidence is modest (rated 2/5), and more high-quality, strain-specific research is needed before routine use can be recommended.

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