Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus rhamnosus has been researched for its potential to prevent and manage eczema (atopic dermatitis), particularly in children. Scientific interest in this probiotic stems from the understanding that gut microbiota can influence immune responses and skin health. Some clinical trials, especially those involving L. rhamnosus GG, have shown modest benefits in reducing the risk of developing eczema when administered to pregnant women and infants at high risk of allergy. For example, a landmark study by Kalliomäki et al. (2001) found a lower incidence of eczema in children who received L. rhamnosus GG compared to placebo. However, not all studies have replicated these results, and meta-analyses report mixed findings, with some showing only minor risk reduction or no significant effect at all. The evidence is stronger for prevention rather than treatment of established eczema. Clinical guidelines, such as those from the World Allergy Organization, suggest there may be a benefit in high-risk populations, but routine use is not universally recommended due to variability in study outcomes and strains used. Overall, the use of L. rhamnosus for eczema is supported by scientific research, but the strength of evidence is modest and not conclusive.

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