Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Black seed (Nigella sativa) has a long history of use in traditional medicine for a variety of skin conditions, including eczema. Traditional systems such as Unani, Ayurveda, and various folk medicines have utilized black seed oil topically for its purported anti-inflammatory and soothing properties. The key active compound, thymoquinone, is believed to contribute to these effects. While several small studies and laboratory experiments have demonstrated anti-inflammatory, antioxidant, and antimicrobial activity of black seed oil, the direct clinical evidence for its effectiveness in treating eczema (atopic dermatitis) in humans remains limited and of low quality. Most available studies are either small pilot trials or animal studies suggesting potential benefits for skin inflammation and barrier repair. For instance, a few studies have reported improvement in symptoms such as itching and lesion severity when black seed oil was applied topically, but these studies often lack rigorous controls or sufficient sample sizes. As a result, the primary justification for using black seed for eczema is based on traditional use and anecdotal evidence, rather than robust scientific validation. More high-quality clinical trials are needed to establish its efficacy and safety for this specific condition.

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