Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bisabolol is a naturally occurring monocyclic sesquiterpene alcohol found in the essential oil of German chamomile (Matricaria recutita). Its use in the management of eczema is supported by both its traditional use in herbal remedies and an emerging body of scientific evidence. Bisabolol is valued for its anti-inflammatory, soothing, and skin barrier-supporting properties, which are particularly relevant in the context of eczema (atopic dermatitis), a condition characterized by inflammation, irritation, and impaired skin barrier function.

Research shows that bisabolol can inhibit the synthesis of pro-inflammatory cytokines and enzymes such as COX-2, which are involved in skin inflammation. Additionally, bisabolol demonstrates antimicrobial properties, which may help reduce secondary infections in compromised skin. In vitro and animal studies suggest that bisabolol can decrease skin inflammation and promote healing of irritated skin. Human clinical data are limited but some small studies and product-based evaluations have shown improvements in skin redness, irritation, and overall comfort when bisabolol-containing creams are applied to eczematous or sensitive skin.

Despite these promising indications, large-scale, high-quality clinical trials specifically targeting eczema are lacking. Most evidence is based on mechanistic studies, small trials, or the inclusion of bisabolol in multi-ingredient formulations. Therefore, while there is a reasonable scientific rationale for its use and some supporting evidence (rating: 2 out of 5), more robust clinical research is needed to fully validate bisabolol as an effective treatment for eczema.

More about bisabolol
More about Eczema

Other ingredients used for Eczema

Other health conditions supported by bisabolol

Products containing bisabolol