Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Baphicacanthus cusia, also known as Indigo naturalis or Qing Dai in traditional Chinese medicine (TCM), has a long history of use in Asia for various dermatological conditions, including eczema. The application of Indigo naturalis for skin diseases like eczema is well documented in classical TCM texts, where it is believed to "clear heat" and "detoxify" the skin. Several modern studies have investigated its active components, such as indirubin and indigo, for their potential anti-inflammatory and immunomodulatory effects. Some small clinical trials and case reports (primarily from East Asia) suggest that topical preparations of Indigo naturalis may reduce symptoms and improve lesions in patients with eczema and other inflammatory skin disorders. However, these studies are generally limited by small sample sizes, lack of rigorous controls, and variability in product formulation. Thus, while there is emerging scientific interest, the dominant justification for its use remains traditional. Evidence quality is moderate at best, and larger, high-quality clinical trials are needed to establish safety and efficacy conclusively.

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