Evidence supporting the use of: Thymoquinone
For the health condition: Dyspepsia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Thymoquinone is a bioactive compound found in Nigella sativa (black seed), which has a long history of use in traditional medicine systems, particularly in Middle Eastern, Indian, and North African cultures. In these traditions, Nigella sativa has been employed for a range of digestive complaints, including dyspepsia (indigestion), often as a carminative or tonic to relieve symptoms such as bloating, gas, and mild stomach discomfort.

While there is a substantial body of preclinical research on thymoquinone's pharmacological properties—such as anti-inflammatory, antioxidant, and gastroprotective effects—there is limited direct scientific evidence specifically validating the use of thymoquinone for dyspepsia in humans. Most clinical studies have focused on black seed oil or Nigella sativa as a whole, rather than isolated thymoquinone, and these studies are generally small and of variable quality. Some animal studies have shown that thymoquinone can protect gastric mucosa and reduce gastric acidity, which could potentially be relevant to dyspepsia, but these findings have not been robustly confirmed in clinical trials targeting dyspepsia.

In summary, the use of thymoquinone for dyspepsia is primarily supported by traditional use of Nigella sativa in folk medicine. Scientific evidence is preliminary and indirect, with insufficient high-quality clinical data to conclusively establish efficacy for this specific condition.

More about Thymoquinone
More about Dyspepsia

Other ingredients used for Dyspepsia

cutch
allspice
aloe vera
green chiretta
apple
artichoke
barberry
basil
myrobalan
berry flavor
betel
bilberry
black pepper
blackberry
rice
chamomile
Coptis chinensis
turmeric
curcumin
dandelion
fennel
flavonols
ginger
goldenseal
heartwood
Indian tinospora
licorice root
marshmallow
mustard seed
oregon grape
peppermint oil
phellodendron amurense
plantain
plum fruit
raspberry
slippery elm bark
sphaeranthus indicus
triphala
gastrodia
cardamom
papaya
Indian bael
neem tree
nut grass
alpinia galangal
clerodendrum indicum
ferula assafoetida
hedychium spicatum
anise
tinospora cordifolia
blackboard tree
caesalpinia crista
fumaria parviflora
swertia
peony
boxthorne
yarrow
prickly ash
myrrh
chrysanthemum
dioscorea
fern
hyacinth bean
sweetgums
morinda
trichosanthes
zanthoxylum
wood betony
white oak
indigo leaves
enzymes blend (proprietary)
geranium
Avens
Angelica
acacia
Agrimony
Achyranthes
Abrus
Amomum
Asafoetida
Ajuga
Anserina
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Alsonia scholaris
Agrimonia pilosa
Asteracea
Ananain
Abuta
Aniseed myrtle
Arisaema
Black Seed
Bai Ji
Bidens pilosa
Blackthorn
Bicarbonate
Blepharis
Belleric myrobalan
Bistort
Butea monosperma
Barleria
Bitter Grass
Bael
Boswellia
Banyan
Bur-Reed
Black Nightshade
Bombax
Bitter principals
Black root
banana
Bergenia
Boerhavia diffusa
Centaury
Cinnamomum
Combretum quadrangulare
Clerodendrum phlomidis
Centaurium erythraea
Citron
Carry Me Seed
Capsaicin
Curcumen
Catechu
Campylandra fimbriata
Colombo
Corktree
Curcuma
Chirata
Costus
Colocynth
Celosia
Dianthrone
Dichrostachys glomerata
Erodium cicutarium
Evodia
Elephant's Head
European-Five Finger Grass
Embelia
Flueggea suffruticosa
Four leaved grass
Goldthread
Genipap
Gnaphalium
Gentianella amarella
Gallotannin
Galangal
Lotus
Little ironweed
Snakeroot (unspecified)

Products containing Thymoquinone

We currently have no products on Caring Sunshine that contain this ingredient.