Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ruta graveolens, commonly known as rue, has a long history of use in traditional herbal medicine systems, particularly in Europe and the Mediterranean, for addressing digestive complaints, including dyspepsia (indigestion). The traditional rationale for its use is based on its reputed carminative, spasmolytic, and bitter properties, which were believed to stimulate appetite, promote bile flow, and relieve gastrointestinal discomfort.

Historical texts, such as those by Dioscorides and Galen, frequently mention rue as a remedy for stomach and digestive issues. In folk medicine, rue has been used to alleviate bloating, gas, and various forms of dyspepsia. However, the scientific evidence supporting these traditional uses is limited. Only a few pharmacological studies have investigated rue's effects on the digestive system, and most research is either in vitro, animal-based, or focused on other potential properties such as anti-inflammatory or antimicrobial actions.

Adverse effects and toxicity are also concerns with rue, as it contains furanocoumarins and alkaloids that can be harmful in larger doses. Therefore, while there is a robust tradition of using rue for dyspepsia, modern scientific validation is lacking, and the evidence remains primarily historical and anecdotal.

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