Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcuminoids, the active polyphenolic compounds found in turmeric (Curcuma longa), have been studied for their potential role in supporting or treating dyspepsia (indigestion). The use of turmeric for gastrointestinal complaints, including dyspepsia, has a long history in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine. However, in recent years, several scientific studies and clinical trials have examined the efficacy of curcuminoids for functional dyspepsia.

Randomized, double-blind, placebo-controlled trials have suggested that turmeric extracts containing curcuminoids can improve symptoms of functional dyspepsia, including pain, fullness, and discomfort. One meta-analysis published in Systematic Reviews (2021) concluded that turmeric and curcumin were associated with significant improvements in dyspepsia symptoms compared to placebo, with a favorable safety profile. Potential mechanisms include anti-inflammatory, antioxidant, and gastroprotective effects, as well as modulation of gastric motility and reduced visceral hypersensitivity.

Despite these findings, the overall quality and sample sizes of available studies are moderate, and further large-scale, high-quality trials are needed for definitive conclusions. The evidence is thus stronger than for many traditional remedies, but not yet robust enough for the highest rating. Current clinical guidelines in some regions consider curcuminoids as a complementary option for dyspepsia when conventional treatments are insufficient or not tolerated.

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