Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Calamus rhizome (Acorus calamus), commonly known as sweet flag, has a long history of use in various traditional systems of medicine—including Ayurveda, Traditional Chinese Medicine, and European herbalism—for the treatment of digestive disorders such as dyspepsia (indigestion). Historical texts describe its application as a carminative (to relieve flatulence), stomachic (to stimulate appetite and gastric function), and spasmolytic (to relieve spasms of the digestive tract). The rhizome is typically used in small quantities, often as part of polyherbal formulations, to support digestion, reduce bloating, and soothe discomfort associated with dyspepsia.

Scientific evidence supporting the efficacy of calamus rhizome for dyspepsia is limited. Some in vitro and animal studies suggest that calamus extracts may influence gastrointestinal motility, have mild antispasmodic effects, and stimulate gastric secretions, potentially explaining its traditional use. However, robust clinical trials in humans are lacking, and safety concerns exist: certain varieties of Acorus calamus contain β-asarone, a compound considered potentially carcinogenic and neurotoxic in high doses. Regulatory agencies in several countries have imposed restrictions on the use of calamus and its extracts for human consumption.

In summary, while the use of calamus rhizome for dyspepsia is well-established in traditional medicine, modern clinical evidence is lacking, and safety concerns limit its recommendation in contemporary practice.

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