Alstonia scholaris, commonly known as the “Devil’s Tree” or “Saptaparna,” is widely used in traditional systems of medicine such as Ayurveda and traditional folk medicine in India and Southeast Asia. Its bark and other parts have been used for a range of gastrointestinal disorders, including dyspepsia (indigestion). The traditional use is based on its reputed properties as a bitter tonic, astringent, and digestive stimulant. Classical Ayurvedic texts and ethnobotanical surveys mention the use of Alstonia scholaris bark decoctions and powders to relieve symptoms of indigestion, flatulence, and loss of appetite. These uses are often attributed to its perceived ability to balance digestive “fire” (Agni) and counteract “Ama” (toxins) in Ayurvedic thought.

However, scientific validation for these specific indications remains limited. While some pharmacological studies have investigated Alstonia scholaris for its anti-microbial, anti-inflammatory, and anti-ulcer activities, direct clinical evidence supporting its efficacy for dyspepsia is lacking. Most studies are either preclinical or focus on related gastrointestinal conditions rather than dyspepsia specifically. Therefore, while the traditional use is well-established, the evidence from modern scientific research is still insufficient to robustly support its use for dyspepsia.