Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Agrimony (Agrimonia eupatoria) has a long history of use in traditional herbal medicine, particularly in European herbalism. It has been employed for a variety of digestive complaints, including dyspepsia (indigestion). Traditional texts and herbal compendia, such as those by Culpeper and in the German Commission E monographs, mention agrimony as a mild astringent and tonic for the digestive tract. Its use was based on observations that its tannin content may help soothe the gut lining, reduce mild inflammation, and support general digestive function.

However, direct scientific evidence supporting agrimony’s efficacy in treating dyspepsia is limited. Most available research focuses on its general anti-inflammatory, astringent, and mild antispasmodic properties, largely observed in vitro or in animal studies. Some laboratory studies have identified the presence of flavonoids, tannins, and other polyphenols that may contribute to its traditional uses. Despite this, there are no robust clinical trials specifically evaluating agrimony for dyspepsia in humans.

In summary, while agrimony’s use for dyspepsia is primarily rooted in traditional herbal medicine and supported by pharmacological plausibility, it lacks substantial scientific validation. Its evidence rating for this indication is therefore modest, reflecting tradition and limited preclinical data rather than high-quality clinical research.

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