Evidence supporting the use of: Green tea
For the health condition: Diabetic Retinopathy

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Green tea (Camellia sinensis) has been studied for its potential benefits in diabetic retinopathy primarily due to its rich content of polyphenols, especially epigallocatechin gallate (EGCG). Several preclinical studies suggest that green tea polyphenols may exert protective effects on the retina by reducing oxidative stress, inhibiting inflammation, and suppressing the formation of advanced glycation end-products (AGEs), all of which are implicated in the pathogenesis of diabetic retinopathy.

Animal studies have shown that EGCG can reduce retinal damage and vascular leakage in diabetic models. For example, research in diabetic rats indicates that green tea extract administration lowers retinal oxidative markers and preserves the integrity of retinal vasculature. Some in vitro studies also suggest that green tea compounds can inhibit retinal cell apoptosis and reduce VEGF (vascular endothelial growth factor) expression, which is associated with abnormal blood vessel growth in diabetic retinopathy.

However, despite these promising findings in animal and cell models, there is a lack of large, well-designed clinical trials in humans directly linking green tea consumption to prevention or treatment of diabetic retinopathy. Most human data are indirect, focusing on green tea’s general benefits on vascular health and glycemic control. Therefore, while there is a scientific rationale and some preclinical evidence (hence the rating of 2), robust clinical validation is lacking at this time.

More about green tea
More about Diabetic Retinopathy

Other health conditions supported by green tea

Acne
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