Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rhamnus nakaharai, a species within the Rhamnus genus, has traditional use in East Asian medicine as a laxative, particularly for constipation. The use of Rhamnus species (such as Rhamnus purshiana—Cascara sagrada—and Rhamnus frangula—Frangula or Buckthorn) is well documented in traditional herbal medicine, with their anthraquinone glycosides believed to stimulate bowel movements. Rhamnus nakaharai specifically has been cited in some Taiwanese and Chinese herbal texts as a purgative for children experiencing constipation, relying on empirical use rather than controlled clinical trials.

However, the available evidence supporting its use in children is limited to historical and ethnobotanical records. There are no high-quality randomized controlled trials or systematic scientific studies directly evaluating Rhamnus nakaharai for pediatric constipation. Most information derives from broader knowledge of anthraquinone-containing plants and their general laxative effects. Some phytochemical studies confirm the presence of anthraquinones in Rhamnus nakaharai, supporting a plausible mechanism, but safety and efficacy in children have not been scientifically validated. As a result, its use remains primarily traditional, with moderate evidence based on long-standing practice rather than robust clinical data.

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