Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus pentosus is a probiotic bacterium that has been investigated for its potential benefits in gastrointestinal health, including the management of constipation in children. The evidence supporting its use for pediatric constipation is emerging but limited. A few clinical trials and studies suggest that certain strains of Lactobacillus pentosus may help improve stool frequency and consistency in children with functional constipation. For example, a randomized controlled trial published in Pediatric Research (2017) found that L. pentosus supplementation improved defecation frequency and reduced abdominal pain in children with constipation, compared to placebo. The proposed mechanisms include modulation of the gut microbiota, enhancement of intestinal motility, and production of short-chain fatty acids, which may soften stools and promote bowel movements.

However, the overall quality and quantity of evidence are still limited. Most studies have small sample sizes, and not all are double-blinded or placebo-controlled. Furthermore, results can vary depending on the specific strain of L. pentosus used, the dosage, and the population studied. No major pediatric gastroenterology guidelines currently recommend L. pentosus specifically for constipation, but probiotics in general are recognized as a potential adjunctive therapy. More robust, larger-scale clinical trials are needed to confirm efficacy and safety in children.

In summary, there is some preliminary scientific evidence supporting the use of Lactobacillus pentosus for childhood constipation, but it is not yet strong or conclusive.

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