Synopsis

Source of validity: Scientific
Rating (out of 5): 3

High amylose polysaccharide, particularly in the form of high-amylose maize starch (HAMS), is scientifically validated as a dietary intervention for constipation, including in children. High amylose starch is a type of resistant starch (RS2), meaning it resists digestion in the small intestine and reaches the colon largely intact. In the colon, it is fermented by the microbiota to produce short-chain fatty acids (SCFAs), particularly butyrate, which have beneficial effects on gut health, motility, and stool consistency.

Clinical studies and randomized controlled trials have investigated the role of resistant starch in managing constipation. For example, some pediatric studies have shown that supplementation with resistant starch improves stool frequency and consistency in children with functional constipation. The mechanism is thought to be due to the increased fecal bulk and enhanced microbial fermentation, which softens stools and promotes more regular bowel movements.

While the evidence base is not as extensive as for some other fiber types (e.g., psyllium), there is growing support from human trials and mechanistic studies for the use of high amylose polysaccharide as a functional ingredient to alleviate childhood constipation. However, more large-scale pediatric-specific trials would be beneficial to further confirm efficacy and optimal dosing.

In summary, high amylose polysaccharide has a moderate level of scientific evidence supporting its use to treat constipation in children, mainly through its function as a fermentable, bulking dietary fiber.

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