Synopsis

Source of validity: Scientific
Rating (out of 5): 4

D-sorbitol is a sugar alcohol that functions as an osmotic laxative and is used to treat constipation in both adults and children. Its mechanism involves drawing water into the large intestine, which softens the stool and promotes bowel movements. Multiple clinical studies and guidelines support its efficacy and safety in pediatric patients.

For instance, the American Academy of Pediatrics and several pediatric gastroenterology guidelines recognize sorbitol as an effective laxative option for children with constipation. Sorbitol is available in liquid form and is sometimes preferred due to its palatability and ease of administration in younger children. Clinical trials have demonstrated that oral sorbitol increases stool frequency and improves stool consistency in children with functional constipation.

Although not as extensively studied as other agents like lactulose or polyethylene glycol (PEG), sorbitol’s laxative properties are well established, and it is included in standard references such as the World Health Organization Model List of Essential Medicines for Children. Adverse effects are generally mild, including flatulence, abdominal discomfort, and diarrhea at higher doses.

In summary, the use of d-sorbitol for treating constipation in children is supported by scientific evidence and clinical experience. It is an accessible, effective, and safe option when used appropriately under medical supervision.

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