Evidence supporting the use of: Bitter Principles
For the health condition: Constipation (children)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Bitter Principles, which refer to a class of plant-derived compounds characterized by their bitter taste (such as those found in gentian, dandelion, or artichoke), have a long history of use in traditional medicine systems for digestive complaints, including constipation. In traditional European herbal medicine, "bitters" are commonly administered to stimulate appetite and enhance digestive function. The rationale is that the bitterness stimulates receptors in the mouth and gastrointestinal tract, triggering reflexes that increase saliva, gastric juice, and bile secretion, thereby promoting gut motility. This traditional use extends to children in some cultures, though with caution regarding dosage and safety.
However, the scientific evidence specifically supporting the use of Bitter Principles for treating constipation in children is limited. Most available studies focus on adults and pertain to general digestive stimulation rather than constipation per se. Clinical trials directly evaluating efficacy in pediatric constipation are lacking, and safety profiles for many bitter herbs in children are not well established. The mechanism by which bitters might help with constipation is plausible—by promoting digestion and mild laxative effects—but direct evidence is insufficient. Therefore, while the use is rooted in tradition, it is not strongly validated by modern clinical research, especially for pediatric populations.
More about Bitter Principles
More about Constipation (children)
Other ingredients used for Constipation (children)
2'-Fucosyllactosealoe vera
apple
apricot
bacillus coagulans
bamboo
basil
beet
myrobalan
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bio ecolian (proprietary)
blackberry
blueberry
bасора
carrot
chamomile
chicory
cinnamon
citrus sinensis (proprietary)
coconut milk
Coptis chinensis
cowage seed
cucumber
turmeric
d-sorbitol
fennel
fiber blend (proprietary)
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
grape
green banana
guar gum
cellulose
Indian tinospora
inulin
isomalto-oligosaccharide
jujube
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus gasseri
lactobacillus reuteri
lemon
mannitol
moringa
nettle
orange
pear
phellodendron amurense
pineapple
plum fruit
pomegranate
potato starch
prebiotic blend (proprietary)
prune
psyllium
pumpkin
raspberry
rhizome
slippery elm bark
sorbitol
spinach
streptococcus thermophilus
tomato
triphala
almond fruit
vegetable and fruit blend (proprietary)
seaweed
watermelon
squawvine
cascara sagrada
tangerine
atractylodes
papaya
mugwort
Indian bael
nut grass
alpinia galangal
anise
punarnava
blackboard tree
root tuber
dioscorea
dodder
sweet flag
polyphenols
senna
peach
indigo leaves
soursop
Agar
Anthraquinone
Ardisia
Amomum
Alexandrian senna
Aloin
Appleblossom Cassia
Asam gelugor
Asteracea
Arabinoxylan
Allium tuberosum
Amor seco
Atractylone
Black Seed
Bifidobacterium
Bifidobacterium adolescentis
Bidens pilosa
Broussonetia
Bishop's Weed
Belleric myrobalan
Bran
Bitter Grass
Bael
Butternut
black salt
Bifidobacterium animalis
Bee products
Bombax
Borassus Palm
Bacteria
Bifidobacteria
Bacillus
Bassia scoparia
Bottle gourd
Borneol
Coconut
Curry leaf
Cascaroside
Cactus
Cynomorium
Citrus
Cantaloupe
Cyclanthera pedata
Chenopodium
Curcuma
Cabbage
Chirata
Clostridium butyricum
Castor Oil
Celosia
Currant
Chondrus
Dianthrone
Date
Eclipta
Fig
Galangal
Phosphate Salt
Rhubarb
Wheat
Zucchini
Other health conditions supported by Bitter Principles
Acid IndigestionAppetite (deficient)
Belching
Circulation (poor)
Colic (adults)
Colic (children)
Constipation (adults)
Constipation (children)
Digestion (poor)
Fatigue
Gall Bladder (sluggish or removed)
Gas and Bloating
Gastritis
Indigestion
Inflammation
Liver Detoxification
Nausea and Vomiting
Sugar Cravings
Ulcers
Wounds and Sores