Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Broussonetia, most commonly referring to Broussonetia papyrifera (paper mulberry), has a history of use in traditional medicine across East Asia. In Traditional Chinese Medicine (TCM), the fruit of Broussonetia papyrifera (known as Chu Shi Zi, 楮实子) has been documented in herbal formularies as having mild laxative properties and is sometimes included in prescriptions aimed at nourishing yin and moistening the intestines to relieve constipation, particularly in older adults or those with yin deficiency. However, the empirical basis for its use is rooted in theory and clinical tradition rather than rigorous scientific validation.

Modern scientific studies specifically investigating the efficacy of Broussonetia (any species or plant part) for treating constipation in adults are lacking. While some laboratory research has focused on the plant’s antioxidant, anti-inflammatory, and neuroprotective effects, there is little direct evidence addressing its impact on gastrointestinal motility or bowel function. Therefore, the evidence supporting its use for constipation is almost entirely traditional, and the quality or quantity of supporting clinical data is minimal. More research, especially well-designed clinical trials, would be needed to substantiate any laxative or stool-softening effects attributed to Broussonetia species.

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