Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium (unspecified species) is used to support or treat constipation in adults, and there is moderate scientific evidence for its efficacy. Several randomized controlled trials and meta-analyses have investigated the effect of Bifidobacterium-containing probiotics on adult constipation. These studies suggest that certain strains of Bifidobacterium, particularly Bifidobacterium lactis (e.g., DN-173 010 and HN019), can improve stool frequency and consistency in constipated adults compared to placebo. Mechanistically, Bifidobacterium species are believed to modulate gut motility, alter the gut microbiota composition, and produce short-chain fatty acids that may promote colonic transit.

However, results are not entirely consistent across all studies, and effectiveness appears to be strain-specific. Systematic reviews and meta-analyses (e.g., Dimidi et al., 2014, American Journal of Clinical Nutrition; Zhang et al., 2020, World Journal of Gastroenterology) generally report a modest but statistically significant benefit for constipation relief with Bifidobacterium-containing probiotics. The evidence base is stronger when specific strains are used and when probiotics are administered for at least 2–4 weeks.

In summary, while not all Bifidobacterium strains are equally effective, and the benefit is generally modest, there is scientific support—though not overwhelming—for the use of certain Bifidobacterium probiotics in managing adult constipation.

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