Evidence supporting the use of: Flavonones (unspecified)
For the health condition: Congestion (sinus)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Flavonones, a subclass of flavonoids found in citrus fruits and some medicinal plants, have been traditionally used in various cultures to alleviate symptoms of sinus congestion and related respiratory discomforts. The traditional rationale behind their use lies in the general belief that plant-derived compounds possess anti-inflammatory and antioxidant properties, potentially reducing swelling and promoting clearer airways. Some herbal remedies, particularly those containing citrus bioflavonoids, have been historically utilized as adjuncts in managing colds or sinus symptoms. However, direct scientific validation for the use of flavonones specifically for sinus congestion is limited. While laboratory and animal studies have shown that certain flavonones (such as hesperidin and naringin) exhibit anti-inflammatory and vasoprotective effects, clinical studies examining their efficacy for sinus congestion in humans are sparse or inconclusive. Most available evidence remains preclinical or anecdotal, and flavonones are not a standard or approved treatment for sinus congestion in modern medicine. Therefore, the use of flavonones for this condition is primarily grounded in traditional practices rather than robust scientific evidence.

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