Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Andrographolide is the main active compound found in Andrographis paniculata, an herb traditionally used in Ayurveda and Traditional Chinese Medicine. Historically, Andrographis has been used to treat a variety of respiratory ailments, including the common cold, flu, fever, and upper respiratory tract infections, which often involve symptoms like nasal congestion. Its use for sinus congestion is primarily rooted in these traditional practices, where it is believed to have anti-inflammatory, antipyretic, and immune-supportive properties. Several published clinical trials and systematic reviews suggest that standardized extracts of Andrographis paniculata may reduce the severity and duration of symptoms associated with upper respiratory tract infections, such as sore throat, cough, and nasal congestion. However, most studies focus on general respiratory infection symptom relief rather than sinus congestion specifically. While there is moderate evidence for its effectiveness in treating the common cold, the direct evidence for sinus congestion (sinusitis) is limited, and the mechanism appears to be through general immune modulation and anti-inflammatory effects rather than targeted decongestant action. Thus, the use of andrographolide for sinus congestion is supported primarily by tradition, with some emerging but not definitive scientific support.

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More about Congestion (sinus)

Other ingredients used for Congestion (sinus)

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