Synopsis

Source of validity: Scientific
Rating (out of 5): 4

N-acetyl-cysteine (NAC) is scientifically validated for use in treating or supporting bronchial congestion. NAC acts as a mucolytic agent, meaning it helps break down and thin mucus, making it easier to clear from the airways. This effect is due to its ability to disrupt disulfide bonds in mucoproteins, thereby reducing mucus viscosity. Clinical studies and systematic reviews have demonstrated that NAC can reduce the frequency and severity of exacerbations in chronic bronchitis and chronic obstructive pulmonary disease (COPD), both of which often involve significant bronchial congestion. For example, a meta-analysis published in the European Respiratory Review (2017) found that NAC supplementation significantly reduced the risk of exacerbations and improved overall symptoms in chronic bronchitis and COPD patients. NAC is also commonly used in hospital settings as an inhaled or oral agent for managing thick pulmonary secretions in conditions like cystic fibrosis, bronchiectasis, and other respiratory illnesses where mucus buildup is problematic. While most studies focus on chronic conditions, its mucolytic effects are also beneficial in acute settings, such as during respiratory infections with excessive mucus production. Overall, the evidence base for NAC’s use in bronchial congestion is robust, with decades of clinical use and several well-conducted trials supporting its efficacy.

More about N-acetyl-cysteine (NAC)
More about Congestion (bronchial)

Other ingredients used for Congestion (bronchial)

Other health conditions supported by N-acetyl-cysteine (NAC)

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