Evidence supporting the use of: Prickly Ash (Unspecified)
For the health condition: Colds (with fever)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Prickly Ash, which generally refers to species in the genus Zanthoxylum (such as Zanthoxylum americanum or Zanthoxylum clava-herculis), has a longstanding history of use in traditional herbal medicine in North America and parts of Asia. Traditionally, Native American and early European settlers used various parts of the Prickly Ash tree (bark and berries) to address ailments such as colds, fevers, and sore throats. The use for "colds with fever" specifically is rooted in its reputation as a warming, stimulating herb believed to promote circulation, induce sweating, and thus help "break" a fever. While ethnobotanical records and herbal texts from the 19th and early 20th centuries frequently mention Prickly Ash for this purpose, there is little to no modern clinical research validating these uses. Some phytochemical studies have identified active compounds like alkaloids and essential oils, which may have mild stimulant or antimicrobial properties, but direct evidence of efficacy in treating colds or fevers is lacking. The evidence rating is 2, reflecting a strong traditional use but poor scientific substantiation. Adverse effects are rare but possible, and it should not be used as a substitute for proven therapies in serious infections.

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