Evidence supporting the use of: Phenylpropanoids (unspecified)
For the health condition: Colds (with fever)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phenylpropanoids are a broad class of plant secondary metabolites, many of which are present in traditional herbal medicines used for treating colds with fever. While "phenylpropanoids (unspecified)" is not a specific compound, several well-known phenylpropanoids (such as eugenol, cinnamaldehyde, and anethole) are found in herbs commonly used in traditional medicine for colds, such as cinnamon, clove, and star anise. Ethnobotanical records indicate the use of these plants for relieving symptoms of cold, including fever, congestion, and sore throat. The rationale is often based on presumed antiviral, anti-inflammatory, or diaphoretic properties attributed to these herbs, and by extension, to their phenylpropanoid constituents.

However, direct scientific evidence linking unspecified phenylpropanoids as a group to the treatment or support of colds with fever is limited. Some individual phenylpropanoids have demonstrated modest antiviral or anti-inflammatory activity in laboratory studies, but clinical trials in humans are sparse and do not generally focus on the class as a whole. Thus, the use of phenylpropanoids in this context is primarily rooted in traditional practice, with a limited scientific basis mainly from in vitro studies rather than robust clinical data.

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