Evidence supporting the use of: Grape
For the health condition: Colds (with fever)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Grape, particularly in the form of grape juice or whole grapes, has traditionally been used in some cultures as a home remedy to support the body during colds, especially when accompanied by fever. The use is primarily based on the pleasant taste, high water content, and the presence of natural sugars, which can provide some energy and hydration during illness. Historically, grapes have also been valued for their antioxidant content—especially polyphenols like resveratrol—which may be perceived as beneficial for general immune support. However, there is minimal direct scientific evidence that grape or grape juice has a clinically significant effect on colds or fever. Most of the purported benefits are extrapolated from the fruit’s general nutritional profile and antioxidant content, rather than from controlled trials in the context of respiratory infections. Some limited in vitro studies suggest that grape polyphenols may have antiviral or anti-inflammatory effects, but these findings have not been robustly translated into human clinical outcomes for colds. In summary, the use of grape for colds with fever is justified by tradition and general nutritional support rather than by strong scientific evidence for efficacy against cold viruses or fever reduction.

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