Synopsis

Source of validity: Traditional
Rating (out of 5): 1

The use of unspecified Rubiaceae species for the prevention or treatment of colds is primarily traditional, rather than scientifically validated. The Rubiaceae family is extensive, including plants such as Coffea (coffee), Cinchona (source of quinine), and Morinda citrifolia (noni). In various traditional medicinal systems, some Rubiaceae species have been used for their purported immune-boosting or anti-infective properties. For example, Morinda citrifolia (noni) fruit juice has been traditionally consumed in Polynesian medicine for a range of ailments, including respiratory complaints, though not specifically or universally for the prevention of the common cold.

Scientific studies directly supporting the use of unspecified Rubiaceae species for cold prevention are lacking. Some extracts from certain Rubiaceae plants have demonstrated antimicrobial or anti-inflammatory properties in vitro, but these findings are preliminary and do not specifically address cold prevention in humans. Moreover, most research focuses on isolated compounds such as quinine (antimalarial) rather than effects on viral respiratory infections. Therefore, while there is a basis for traditional use in some cultures, robust scientific evidence is absent, and the overall evidence rating for this use is low.

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