Lo Han Guo, also known as monk fruit (Siraitia grosvenorii), has a long history of use in Traditional Chinese Medicine (TCM) for treating respiratory conditions, including colds, sore throat, and cough. In traditional Chinese practice, Lo Han Guo is believed to have cooling and moistening effects, which are thought to help soothe the throat and clear “heat” from the lungs. Classical herbal texts and modern TCM resources often mention its use for relieving symptoms like dry cough, hoarseness, and thirst associated with upper respiratory tract infections and colds.

However, scientific evidence supporting these traditional uses is limited. While Lo Han Guo is known to contain mogrosides (sweet compounds with antioxidant properties), there is little direct clinical research on its effectiveness for cold prevention or treatment in humans. Most available studies focus on its sweetening properties and safety rather than therapeutic benefits for respiratory infections. Some in vitro and animal studies suggest anti-inflammatory and antioxidant effects, which could theoretically support immune health, but these findings have not been translated into robust clinical evidence for colds.

In summary, Lo Han Guo’s use for colds is primarily supported by traditional use in Chinese medicine, with limited scientific validation.