Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Iridoids are a class of phytochemicals found in various medicinal plants, such as elderberry (Sambucus nigra), olive (Olea europaea), and valerian (Valeriana officinalis). Their use in the prevention and management of colds is rooted primarily in traditional herbal medicine practices. In systems like Traditional Chinese Medicine and European folk medicine, iridoid-containing plants have been used for centuries to "strengthen the body's defenses" and support general health during seasonal illness. For example, elderberry preparations, which contain iridoids alongside other bioactive compounds, have been a popular remedy for colds and flu-like symptoms.

However, scientific validation specifically linking iridoids themselves to cold prevention is limited. Most modern research on cold prevention has focused on vitamins (like vitamin C), minerals (like zinc), or other plant compounds such as flavonoids and polyphenols. While some in vitro and animal studies suggest iridoids possess anti-inflammatory or immune-modulating properties, direct clinical evidence supporting their efficacy in cold prevention in humans is lacking. Thus, the rationale for using iridoids for this purpose relies mainly on traditional use and anecdotal reports rather than robust scientific trials.

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