Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Black seed (Nigella sativa) has a long history of traditional use in various cultures, particularly in Middle Eastern and South Asian medicine, for supporting immune health and preventing colds. Historical records and ancient texts—including those from traditional Unani, Ayurveda, and Islamic medicine—describe black seed as a remedy for a variety of ailments, with frequent mention of its use for respiratory complaints such as coughs, congestion, and viral infections. The seeds and their oil were commonly consumed or used in home remedies intended to strengthen the body against colds and other seasonal illnesses.

Modern scientific research into black seed’s effects on the immune system is ongoing, but there is only limited direct clinical evidence regarding its efficacy for cold prevention. Some small-scale studies and in vitro research suggest that thymoquinone, a major active compound in black seed, exhibits immunomodulatory and anti-inflammatory properties. A few human studies have suggested possible benefits for general immune support; however, robust clinical trials specifically investigating black seed’s effectiveness in preventing common colds are lacking. Thus, while its use for colds is well established in traditional medicine, scientific validation is limited and the evidence is best classified as low to moderate.

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