Evidence supporting the use of: Prickly Ash Bark
For the health condition: Colds (general)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Prickly Ash Bark (Zanthoxylum americanum) has a longstanding history of traditional use in North America, particularly among Native American tribes and in early Western herbalism, for the symptomatic relief of colds and related respiratory ailments. It was commonly prepared as a tea, tincture, or decoction, with practitioners believing it could stimulate circulation, promote perspiration, and help the body "break" a fever or clear congestion. The bark was sometimes referred to as the "toothache tree" for its numbing effects, but it was also valued for its warming, diaphoretic actions, which were thought to be beneficial during colds.
However, modern scientific validation for these uses is extremely limited. While the bark contains various alkaloids, essential oils, and coumarins with mild antimicrobial or circulatory effects in vitro, there is insufficient clinical evidence to support its effectiveness specifically for treating or shortening the duration of the common cold. Most references to Prickly Ash Bark for this purpose are found in ethnobotanical texts and historical materia medica, rather than in peer-reviewed scientific research. As such, its reputation for cold relief is grounded in traditional herbal practice rather than validated by rigorous modern science.
Other ingredients used for Colds (general)
allspicealoe vera
green chiretta
anthocyanins
apple
arabinogalactan
astragalus
waterhyssop
bamboo
barberry
basil
benegut perilla (proprietary)
berry flavor
beta-pinene
black cumin
black currant
black garlic
black pepper
radish
black tea
blackberry
blueberry
bupleurum falcatum
burdock
bасора
capsaicinoids
carrot
cassia bark
caterpillar mushroom
chamomile
cinnamon
citrus oil
citrus sinensis (proprietary)
clove
coconut milk
colostrum
turmeric
dog rose
echinacea purpurea
elderberry
forsythia
garlic bulb
ginger
ginseng
gooseberry
grape
greek mountain tea
onion
green tea
greens blend (proprietary)
horseradish
Indian tinospora
honeysuckle
jujube
l-cysteine
lactobacillus fermentum
lactiplantibacillus plantarum
lactobacillus reuteri
lemon
licorice root
lovage
lychee
marshmallow
mastic gum
milk
moringa
mustard seed
nettle
spruce
orange
oregano
oregon grape
pear
perilla
phellodendron amurense
phenolic acids
pineapple
plantain
plum fruit
pomegranate
pumpkin
quail egg
quercetin
raspberry
redcurrant
reishi mushroom
rhizome
rose hips
rosemary
sage
schizonepeta
scrophularia root
spearmint leaf
sphaeranthus indicus
spirulina
thyme
vegetable blend (proprietary)
vitamin B
vitamin C
vitamin D
wasabia japonica
water
yeast
zinc
sarsaparilla
squawvine
boneset
tangerine
typhonium
xanthium (cockleburs)
hyssop
cardamom
atractylodes
papaya
capsicum
mugwort
Indian bael
neem tree
nut grass
alpinia galangal
ferula assafoetida
pistacia integerrima gall
commiphora
tinospora cordifolia
blackboard tree
bee pollen
peony
lingusticum wallichii
boxthorne
buckthorn
lemongrass
yerba santa
chrysanthemum
siler root
flowering quince
dodder
sweet flag
hyacinth bean
morinda
trichosanthes
zanthoxylum
birch
dulse leaf
purslane
fulvic acid
eucalyptus
menthol oil
aster root
peach
paw paw
abies spectabilis
horehound
Sichuan pepper
algae
indigo leaves
cayenne pepper
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alcohol
Ash
Aralia
Avens
Apple Cider Vinegar
Agastache
Alpha-terpineol
Ardisia
Angelica
acacia
Allicin
Anamu
Abrus
Amomum
Asarum heterotropoides
Aconite
Ajuga
Andrographolide
Aerva lanata
American Liverleaf
Asam gelugor
Andrographis
Asteracea
Allyl Sulfide
allyl isothiocyanate
Alliin
Allium tuberosum
Amor seco
Arani
Atractylone
Bee Propolis
Black Seed
Bermuda Grass
Baikal Skullcap
Baphicacanthus cusia
Bidens pilosa
Blackthorn
Broussonetia
Blepharis
Balsam
Bishop's Weed
Bayleaf
Butea monosperma
Black galingale
Barleria
Bitter Grass
Bougainvillea
Bee hive
Bael
berry
Baccharoides anthelmintica
Banyan
Bur-Reed
Bioflavonoids
black salt
Bee products
Black Nightshade
Bombax
Borassus Palm
Buddha's Hand
Borassus aethiopum
Bitter principals
Bupleurum
Bassia scoparia
Belamcanda
Boerhavia diffusa
Borneol
Cumin
Camellia sinensis
Coconut
Chinese Silkvine
Curry leaf
Cinnamomum
Chinese Mountain Ant
Clerodendrum trichotomum
Cloudberry
coconut oil
Coriander
Chive
Carvacrol
Capillary Artemisia
Citron
Curcuminoid
Citrus
Cineole
Capsaicin
Cajuput
Chinese Raisintree
Chlorophytum
Cowherb
Curcumen
Cistus
Common madia
Curcuma
Cowslip
Calamus
Coin-leaf desmodium
Cinnamaldehyde
Costus
Carthamus
cola nut
Celosia
Culvers Root
Currant
Chrysophanics
Chondrus
Dianthus
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dragonhead
Deoxyandrographolides
David's Milkberry
Desmodium
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
European Elder
Eclipta
Echinacea
Elder
Embelia
Goldthread
Garlic
Lotus
Little ironweed
Mustard
Mallow
Potato
Rose
Spikenard
Sandalwood
Squash
Sumac
Vervain
Zucchini
Other health conditions supported by Prickly Ash Bark
Abdominal PainAcid Indigestion
Angina
Appetite (deficient)
Arthritis
Asthma
Backache
Belching
Blood Clots (prevention of)
Bronchitis
Bruises (healing)
Canker Sores
Cardiovascular Disease
Chest Pain
Chills
Circulation (poor)
Colds (general)
Congestion
Congestion (bronchial)
Congestion (lungs)
Constipation (adults)
Cuts
Diarrhea
Digestion (poor)
Edema
Fever
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Headache (general)
Heart (weakness)
Hemorrhoids
Indigestion
Inflammation
Jaundice (adults)
Laryngitis
Liver Detoxification
Menstrual Irregularity
Muscle Tone (lack of)
Nausea and Vomiting