Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Polygonum is a large genus of plants commonly known as knotweeds, with species such as Polygonum cuspidatum (Japanese knotweed) and Polygonum aviculare (common knotgrass) used in traditional medicine across Asia and Europe. In traditional Chinese medicine, certain Polygonum species have been employed to manage symptoms of colds and other respiratory ailments, often due to their purported "clearing heat" and "detoxifying" properties. Folk uses generally involve decoctions or teas made from aerial parts or roots. However, scientific validation of antiviral effects specifically against cold-causing viruses (chiefly rhinoviruses and coronaviruses) is limited. Some in vitro studies have identified antiviral activity in extracts from related species (such as Polygonum cuspidatum and its constituent resveratrol) against influenza and herpes viruses, but direct evidence in the context of common cold viruses is lacking. Thus, while Polygonum's use for colds has a basis in traditional practice and there are some preliminary studies showing antiviral potential, these do not yet provide robust clinical support for its efficacy against colds specifically. Overall, the evidence supporting Polygonum for treating colds is primarily traditional, with low to moderate scientific backing.

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