Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bioflavonoids, a group of plant-derived compounds found in fruits and vegetables, have a long history of use in traditional and folk medicine for supporting general immunity and treating colds. Their use for colds is primarily based on their antioxidant and purported anti-inflammatory properties, which are believed in traditional systems to help the body resist infections, including viral ones like the common cold. Some traditional remedies include citrus bioflavonoids (from oranges, lemons, etc.) taken alongside vitamin C for enhanced effect. However, scientific validation for a direct antiviral action against cold viruses (such as rhinovirus or coronavirus) is limited and inconclusive. A few laboratory studies suggest that certain flavonoids can inhibit viral replication or modulate immune responses, but these results have not consistently translated into clinically meaningful outcomes in humans. A small number of clinical trials have examined flavonoid supplementation for respiratory tract infections with mixed results—some showing a reduction in incidence or duration, while others show no effect. Major health authorities do not currently recommend bioflavonoids for the prevention or treatment of the common cold. Thus, while traditional use is common and some weak evidence exists, robust scientific support is lacking.

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