Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Baphicacanthus cusia, also known as Indigofera cusia or "Qing Dai" in traditional Chinese medicine (TCM), has been historically used for various ailments, including fever and viral infections. Modern research offers some scientific support for its antiviral properties, particularly relevant to colds. Several in vitro and in vivo studies have demonstrated that extracts from B. cusia possess antiviral activity against a range of viruses, including influenza virus, which is one of the primary causes of the common cold.

Studies have identified compounds such as indirubin and indigo in B. cusia that may contribute to its antiviral effects. For example, research published in peer-reviewed journals has shown that ethanol and aqueous extracts of B. cusia can inhibit viral replication and reduce virus-induced cytopathic effects in cell cultures. Some animal studies also report reduced severity of symptoms when treated with B. cusia extracts.

Despite promising laboratory results, high-quality clinical trials in humans are limited or lacking. Most available evidence is preclinical, and while it supports the potential antiviral activity of B. cusia, more rigorous human studies are needed to establish its efficacy and safety for treating or preventing the common cold.

In summary, there is scientific evidence—mostly from laboratory and animal studies—suggesting B. cusia may have antiviral effects relevant to colds, but definitive clinical validation is not yet available. The evidence level is moderate (3/5), reflecting promising but preliminary findings.

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