Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Ardisia species, such as Ardisia japonica and Ardisia crenata, have been used in traditional medicine systems, particularly in East Asia, for a variety of ailments, including chest pain. The use of Ardisia for chest pain is primarily rooted in traditional Chinese medicine (TCM), where it is believed to "invigorate blood," "dispel blood stasis," and relieve pain. In TCM literature, chest pain is often associated with blood stasis or obstruction, and herbs like Ardisia are employed as part of multi-herb formulations to address these underlying concepts.

However, scientific studies directly evaluating Ardisia species for chest pain (specifically angina, cardiac pain, or non-cardiac chest pain) are extremely limited. Most research on Ardisia has focused on its anti-inflammatory, antioxidant, and anticancer properties, with only a few animal studies or in vitro experiments exploring cardiovascular effects, and none providing robust evidence for efficacy in chest pain management in humans. Consequently, the evidence for its use in chest pain is largely traditional, with little to no modern clinical validation. The rating of 1 reflects the presence of some preclinical pharmacological rationale but an absence of clinical trials or rigorous scientific support for this specific indication.

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