Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex negundo, also known as the Chinese chaste tree or Nirgundi, has a long history of use in traditional medicine systems, particularly Ayurveda and traditional Chinese medicine. It is commonly used for its anti-inflammatory, analgesic, and antimicrobial properties. In the context of canker sores (aphthous ulcers), traditional texts often recommend topical application or mouth rinses of Vitex negundo leaf extracts to reduce pain and promote healing, likely due to its anti-inflammatory activity.

However, direct scientific studies investigating the efficacy of Vitex negundo specifically for canker sores are limited. Most available evidence is anecdotal or based on in vitro studies that demonstrate antimicrobial and anti-inflammatory effects, which could theoretically benefit oral ulcers. A few ethnobotanical surveys in India have documented its traditional use for mouth ulcers, but rigorous clinical trials supporting its effectiveness for this indication are lacking.

In summary, the use of Vitex negundo for canker sores is primarily justified by traditional practices, with limited scientific validation. More high-quality human studies would be necessary to substantiate its therapeutic role for this specific condition.

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