Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin B6 (pyridoxine) has been traditionally used in some cultures to help manage canker sores (aphthous ulcers), largely based on the general belief that B vitamins play a role in oral and mucosal health. Several older studies and anecdotal reports from the mid-20th century suggested that deficiencies in B vitamins, including B6, may be associated with an increased frequency of canker sores. However, these findings were often based on small sample sizes, uncontrolled trials, or case reports, and many did not isolate B6 from other B vitamins in supplementation regimens.

There is limited scientific validation for the use of vitamin B6 alone in the treatment or prevention of canker sores. Most modern clinical studies either examine multivitamin B complexes or focus on deficiencies of vitamin B12 or folate, which have stronger evidence for a connection to recurrent aphthous stomatitis. Reviews and guidelines generally do not recommend vitamin B6 supplementation specifically for canker sores unless a deficiency is detected.

In summary, while the use of vitamin B6 for canker sores is rooted in traditional practices and some historical observations, there is only weak scientific support for its efficacy. More robust clinical trials would be needed to justify its routine use for this condition.

More about Vitamin B6 (not specified)
More about Canker Sores

Other ingredients used for Canker Sores

Other health conditions supported by Vitamin B6 (not specified)

Products containing Vitamin B6 (not specified)