Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B5, also known as calcium pantothenate, has been investigated for its potential role in supporting or treating canker sores (aphthous ulcers). The rationale stems from the broader observation that deficiencies in various B-vitamins have been associated with an increased risk of recurrent mouth ulcers. However, among the B-vitamins, the strongest evidence exists for B12, folate, and sometimes B6, rather than B5 specifically.

There is limited but suggestive scientific evidence for the use of vitamin B5 in this context. A small number of studies and case reports suggest that vitamin B5 supplementation may reduce the frequency or severity of canker sores, but these are neither numerous nor large-scale. For example, a randomized, double-blind, placebo-controlled study published in 1997 (Journal of Oral Pathology & Medicine) found that a combination of B-vitamins including B5 reduced healing time of aphthous ulcers compared to placebo, but B5 alone was not isolated as the active component. Another small trial from the 1970s reported benefit with B5, but methodological limitations reduce its reliability.

Overall, while there is some scientific basis for the use of vitamin B5 in the management of canker sores, the evidence is weak and not definitive. Its use is sometimes supported in the context of general B-complex supplementation rather than as a targeted therapy. Well-designed, large-scale clinical trials are lacking. Therefore, the evidence rating for B5 in this context is low (2/5).

More about Vitamin B5 (calcium pantothenate)
More about Canker Sores

Other ingredients used for Canker Sores

Aloe vera
bamboo
basil
myrobalan
betel
bisabolol
blackberry
bасора
chamomile
clove
coating
coconut milk
Coptis chinensis
curcumin
dog rose
folate
ginger
horseradish
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
magnesium
milk
mustard seed
spruce
omega-3 fatty acids
oregano
oregon grape
parsley
Peppermint
pineapple
plantain
rhizome
sage
schizonepeta
scrophularia root
slippery elm bark
sphaeranthus indicus
thyme
triphala
vitamin B12
vitamin C
zinc
yellow root
squawvine
chickweed
typhonium
xanthium (cockleburs)
papaya
neem tree
nut grass
clerodendrum indicum
ferula assafoetida
commiphora
blackboard tree
boxthorne
buckthorn
lemongrass
myrrh
siler root
hyacinth bean
morinda
oriental arborvitae
trichosanthes
zanthoxylum
sheep's sorrel
eucalyptus
menthol oil
aster root
paw paw
herbal blend (proprietary)
indigo leaves
Ash
Avens
Agastache
Ardisia
Acacia
Agrimony
Achyranthes
Anamu
American Liverleaf
Agrimonia pilosa
Asteracea
Acemannan
Amor seco
Arisaema
Bee Propolis
Bermuda Grass
Blue Flag
Bai Ji
Baphicacanthus cusia
Bidens pilosa
Blackthorn
Bicarbonate
Balsam
Bishop's Weed
Bayleaf
Black galingale
Barleria
Bitter Grass
Bloodroot
Banyan
Bee products
Black Nightshade
Bombax
Borassus aethiopum
Bacteria
Bassia scoparia
Borneol
Coconut
Curry leaf
Calendula
Clerodendrum trichotomum
Chlorophyllin
Carvacrol
Capillary Artemisia
Citron
Capsaicin
Cajuput
Chinese Raisintree
Cowherb
Centipeda
Cistus
Corktree
Collinsonia
Copaiba Oil
Celosia
Chrysophanics
Dianthus
DIVI-DIVI
Dragonhead
David's Milkberry
European Elder
Eupolyphaga sinensis
Eclipta
Essential Oil Blend
Euphorbia
European-Five Finger Grass
Embelia
Eugenol
Flueggea suffruticosa
Fuchsia
Fang-Feng
Ficus simplicissima
Frankincense
Gnaphalium
Glycolic acid
Guava
Giant Blazingstar
Glechoma hederacea
Gallotannin
Galangal
Guazuma ulmifolia
Honey
Heal-All
Helicteres isora
Henna
Herb Robert
Horsemint
Huang Hua
Indian Nightshade
Iridoid glycosides
Indian Coraltree
Long Pepper
Indian Kinotree
Indian Fagonia
Lime
Lebbek
Ledebouriella
Lesser speargrass
Litsea
Luffa
Lodhtree
Lysozyme
Labrador Tea
Little ironweed
Lysimachia
Mustard
Mineral ascorbate
Marjoram
Mallow
Melia
Malva sylvestris
Matico
Matapalo Tree
Momordica
Marigold
Manzanita
Macaranga indica
Nardostachys
Naphthoquinones
Nutmeg
Nimbidin
Oak
Osha
Orris
Onosma bracteatum
Oxystelma
Propolis
Phyllanthus
Premna
Pagoda Tree
Plantago
Pluchea
Prunus
Pepper
Paris polyphylla
Pansit-pansitan
Pyrrosia
Pentatropis capensis
portulaca
Piper nigrum
Patrinia
Physalis angulata
Papayotin
Petiveria
Plectranthus amboinicus
Quisqualis
Rue
Rubus
Resin
Rose
Rhus coriaria
Spilanthes
Sichuan Lovage
Sicklepod
Sinapis arvensis
Sophora
Sesbania
Spanish Needle
Smartweed
Salvia
Snakeroot
Solanum indicum
Sanguisorba
Slippery Elm
Sagebrush
Sandalwood
Scabrous Gentian
Stereospermum
Sumac
Sulfur
Sweet Bay
Terpenoids
Thymus
Tamaricaceae
Thymol
Tansy
Tagetes
Tamarind
Varuna
Violet
Viola
Water Pepper
Winter Begonia
Winter Savory
Yellow-Fruit Nightshade
Zingiberene

Other health conditions supported by Vitamin B5 (calcium pantothenate)

Acne
Burning Feet or Hands
Canker Sores
Convalescence
Dermatitis
Hair (loss or thinning)
Stress
Wounds and Sores

Products containing Vitamin B5 (calcium pantothenate)

We currently have no products on Caring Sunshine that contain this ingredient.