Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rhizomes from certain plants, especially Glycyrrhiza glabra (licorice root), have been traditionally used to treat or support healing of canker sores (aphthous ulcers). The use of rhizomes for canker sores is primarily rooted in traditional herbal medicine practices, particularly in regions such as Asia and the Middle East. Historical texts and ethnobotanical records mention the topical application or oral rinses prepared from licorice rhizome to reduce pain and inflammation associated with canker sores. The purported mechanism is often attributed to glycyrrhizin and other bioactive compounds found in the rhizome, which are thought to possess anti-inflammatory and soothing properties. While a few small clinical studies and case reports suggest that preparations containing licorice root extract may modestly reduce healing time and discomfort, the scientific evidence remains limited and not robust enough for broad clinical endorsement. There is a lack of large, high-quality randomized controlled trials to firmly establish efficacy. Other rhizomes, such as turmeric (Curcuma longa), have also been used traditionally for oral lesions, but again, strong clinical evidence is lacking. In conclusion, the use of rhizome for canker sores is justified by traditional use with some preliminary scientific support, but the overall evidence level is limited and more rigorous research is needed.

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