Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Propolis, a resinous substance collected by bees, has been traditionally used for various oral and skin ailments. In recent years, scientific studies have investigated its potential in supporting or treating canker sores (aphthous ulcers). Several randomized controlled trials and in vitro studies suggest that propolis possesses anti-inflammatory, antimicrobial, and wound-healing properties, which are beneficial in managing canker sores. A 2007 double-blind, placebo-controlled study published in Phytotherapy Research found that a propolis extract decreased the frequency of outbreaks and promoted faster healing of recurrent aphthous ulcers compared to placebo. Other studies have demonstrated that propolis mouthwashes or topical preparations can reduce pain, ulcer size, and healing time, likely due to its flavonoid content and immunomodulatory effects. However, while these findings are promising, the overall quality and size of the studies are moderate, and there is variability in the preparations and dosages used in research. Systematic reviews note that more high-quality, large-scale clinical trials are needed to firmly establish efficacy and optimal usage protocols. In summary, there is scientific evidence supporting the use of propolis in canker sores, but the evidence is not yet strong enough for unequivocal clinical recommendations.

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