Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Premna species, particularly Premna serratifolia (commonly known as "Agnimantha" in Ayurveda), have a long history of use in traditional medicine systems such as Ayurveda and traditional folk medicine in parts of Asia. In these systems, Premna is considered to possess anti-inflammatory, antimicrobial, and wound-healing properties, which are believed to aid in the treatment of various oral conditions, including canker sores (aphthous ulcers). Traditional preparations often involve using decoctions or pastes of Premna leaves or bark applied directly to the affected area to promote healing and reduce pain or inflammation.

However, while there are studies on the general antimicrobial and anti-inflammatory activities of some Premna extracts, there is a lack of direct scientific studies specifically evaluating Premna’s efficacy for the treatment of canker sores in humans. The evidence supporting its use for canker sores is largely anecdotal and rooted in traditional practices rather than robust clinical research. As such, the rating is low (1), reflecting the predominance of tradition-based evidence and the scarcity of scientific validation for this particular indication.

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