Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Physalis angulata, commonly known as cutleaf groundcherry, has a history of use in traditional medicine, particularly in tropical and subtropical regions. Traditional healers have employed parts of the plant, such as leaves and fruits, for various inflammatory and infectious conditions, including oral ulcers like canker sores (aphthous ulcers). The rationale is largely based on the plant’s reputed anti-inflammatory and antimicrobial properties. Folk remedies in regions such as South America and Asia have involved topical application or rinsing with decoctions made from the plant to relieve pain and promote healing of mouth sores.

However, there is limited scientific research directly investigating the efficacy of Physalis angulata specifically for canker sores. Some laboratory and animal studies have shown that extracts of the plant possess anti-inflammatory, antioxidant, and antimicrobial activities, which could theoretically benefit oral ulcerations. Despite this, clinical trials or robust studies evaluating its direct use for canker sores in humans are lacking. Thus, the evidence supporting its use is primarily traditional, with only indirect scientific support based on its general pharmacological properties, not on targeted clinical research for canker sores.

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