Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Omega-3 fatty acids have some scientific evidence supporting their use in the management of canker sores (aphthous ulcers), although the data is still limited and not robust. Omega-3s, which include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are well-known for their anti-inflammatory properties. The theoretical rationale for their use in canker sores stems from the inflammatory nature of these oral lesions. A few small clinical studies and case reports have suggested that omega-3 supplementation may help reduce the frequency, duration, or severity of canker sores, likely by modulating the inflammatory response and supporting mucosal healing. For example, a small randomized controlled trial published in the "Journal of Oral Pathology & Medicine" (2020) found that patients who took omega-3 supplements (1,000 mg/day) for six months experienced a statistically significant reduction in the recurrence and pain of aphthous ulcers compared to placebo. Other studies have reported modest improvements in oral ulcer healing rates with omega-3 supplementation. However, these studies are limited by small sample sizes and short durations. While there is some emerging evidence, it is not yet strong enough to be considered standard therapy, and more large-scale, high-quality trials are needed. Thus, the evidence rating is 2/5, indicating limited but promising scientific support, primarily due to the biologically plausible anti-inflammatory effects of omega-3 fatty acids and preliminary clinical data.

More about omega-3 fatty acids
More about Canker Sores

Other ingredients used for Canker Sores

Other health conditions supported by omega-3 fatty acids

Products containing omega-3 fatty acids

Nature's Sunshine Flax Seed Oil (With Lignans)