Evidence supporting the use of: Lactobacillus salivarius
For the health condition: Canker Sores

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus salivarius is a probiotic bacterium that has been studied for its potential role in supporting oral health, including the management of canker sores (recurrent aphthous stomatitis, RAS). There is a limited but growing body of scientific evidence suggesting that certain probiotic strains, including L. salivarius, may help reduce the frequency and severity of canker sores. The proposed mechanism is based on the ability of probiotics to modulate the oral microbiome, enhance mucosal immunity, and inhibit the growth of pathogenic bacteria that may contribute to ulcer formation or persistence.

Several small clinical studies and pilot trials have indicated that oral administration of L. salivarius, either as lozenges or tablets, can lead to a reduction in the number and duration of canker sore episodes compared to placebo. For example, a randomized controlled trial published in Journal of Oral Pathology & Medicine (2017) found that daily supplementation with L. salivarius WB21 significantly reduced the number of new aphthous ulcers over a 3-month period. However, these studies often have small sample sizes and short follow-up periods, and not all have shown consistent benefit.

In summary, while there is emerging scientific validation for the use of L. salivarius in managing canker sores, the evidence remains preliminary, and larger, well-designed studies are needed before it can be recommended with strong confidence. As such, the quality of evidence supporting its use is currently moderate to low (rated 2/5).

More about lactobacillus salivarius
More about Canker Sores

Other ingredients used for Canker Sores

aloe vera
bamboo
basil
myrobalan
betel
bisabolol
blackberry
bасора
chamomile
clove
coating
coconut milk
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curcumin
dog rose
folate
ginger
horseradish
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
magnesium
milk
mustard seed
spruce
omega-3 fatty acids
oregano
oregon grape
parsley
peppermint oil
pineapple
plantain
rhizome
sage
schizonepeta
scrophularia root
slippery elm bark
sphaeranthus indicus
thyme
triphala
vitamin B12
vitamin C
zinc
yellow root
squawvine
chickweed
typhonium
xanthium (cockleburs)
papaya
neem tree
nut grass
clerodendrum indicum
ferula assafoetida
commiphora
blackboard tree
boxthorne
buckthorn
lemongrass
myrrh
siler root
hyacinth bean
morinda
oriental arborvitae
trichosanthes
zanthoxylum
sheep's sorrel
eucalyptus
menthol oil
aster root
paw paw
herbal blend (proprietary)
indigo leaves
Ash
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Agastache
Ardisia
acacia
Agrimony
Achyranthes
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Agrimonia pilosa
Asteracea
Acemannan
Amor seco
Arisaema
Bee Propolis
Bermuda Grass
Blue Flag
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Bidens pilosa
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Bayleaf
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Barleria
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Banyan
Bee products
Black Nightshade
Bombax
Borassus aethiopum
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Bassia scoparia
Borneol
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Calendula
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Chlorophyllin
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Citron
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Euphorbia
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