Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Cynanchum species have a long history of use in traditional medicine, especially in Chinese herbal practices. Some species, such as Cynanchum atratum and Cynanchum paniculatum, are recorded in Chinese pharmacopoeias for their anti-inflammatory, detoxifying, and healing properties. In traditional Chinese medicine (TCM), these plants are sometimes incorporated into remedies for mouth sores, including canker sores (aphthous ulcers), based on their reputed ability to "clear heat" and "remove toxins" from the body. However, the documentation is mostly anecdotal or based on traditional medical texts rather than on controlled clinical studies. There is a lack of specific, high-quality scientific studies investigating Cynanchum extracts for canker sores. The evidence is therefore considered traditional, and the strength of evidence is low (rated 1), primarily reliant on historic use rather than modern research validation. Safety data is also limited, and some Cynanchum species are known to be toxic in certain contexts, so traditional use should be approached with caution.

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